Bioorganic and Medicinal Chemistry Letters p. 2346 - 2349 (2009)
Update date:2022-08-02
Topics:
Giannini, Giuseppe
Marzi, Mauro
Pezzi, Riccardo
Brunetti, Tiziana
Battistuzzi, Gianfranco
Marzo, Maria Di
Cabri, Walter
Vesci, Loredana
Pisano, Claudio
With the aim to discover novel HDAC inhibitors with high potency and good safety profiles, we have designed a small library based on a N-hydroxy-(4-oxime)-cinnamide scaffold. We describe the synthesis of these novel compounds and some preliminary in vitro
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