Regioselective addition of alcohols to internal 1-aryl-1-alkynes catalyzed by a triangular heterobimetallic Ir2Pd sulfido cluster

Article abstract of DOI:10.1246/cl.1998.717

The triangular heterobimetallic sulfido cluster [(Cp*Ir)₂(μ₃-S)₂PdCl₂] prepared from [PdCl₂(cod)] and [Cp*IrCl(μ-SH)₂IrCp*Cl] was found to catalyze the addition of alcohols to alkynes to give the corresponding ketals. In particular, internal 1-aryl-1-alkynes were transformed into the corresponding 2,2-dialkoxy-1-arylalkanes with high regioselectivity. The analogous Ir₂PtS₂ cluster proved to be much less selective.