Chemical and Pharmaceutical Bulletin p. 1125 - 1129 (1998)
Update date:2022-09-26
Topics:
Kaku, Yumiko
Tsuruoka, Akihiko
Kakinuma, Hiroyuki
Tsukada, Itaru
Yanagisawa, Manabu
Naito, Toshihiko
A novel synthetic route to (2S,3S)-2-(2,4-difluorophenyl)-3-hydroxy-2- methyl-4-(1-(1,2,4-triazolyl))butyronitrile (2), an intermediate for the orally active triazole antifungal agent ER-30346, was developed from methyl S-(+)-3-hydroxy-2-methylpropionate,
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Doi:10.1039/C39880000582
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(1961)Doi:10.1021/jm00125a023
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