Synthesis p. 1136 - 1138 (1987)
Update date:2022-08-05
Topics:
Pooranchand, Dinah
Ila, Hiriyakkanavar
Junjappa, Hiriyakkanavar
The reaction of dimethyl N-aryl- or N-alkylcarbonimidodithioates with aminoacetaldehyde diethyl acetal in refluxing acetic acid affords 1-aryl or 1-alkyl-2-methylthioimidazoles in good yields.Dimethyl N-isopropylcarbonimidodithioate gave 1-isopropylimidazole-2(3H)-thione under similar conditions.
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(1987)Doi:10.1016/j.bmc.2009.03.028
(2009)Doi:10.1002/anie.202013516
(2021)