Reaction of Dimethyl N-Aryl- and N-Alkylcarbonimidodithioates with Aminoacetaldehyde Diethyl Acetal: A Direct Synthesis of 1-Aryl- and 1-Alkyl-2-methylthioimidazoles

DOI: 10.1055/s-1987-28201

Source and publish data:

Synthesis p. 1136 - 1138 (1987)

Update date:2022-08-05

Topics:

Authors:

Pooranchand, Dinah

Ila, Hiriyakkanavar

Junjappa, Hiriyakkanavar

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1987-28201

The reaction of dimethyl N-aryl- or N-alkylcarbonimidodithioates with aminoacetaldehyde diethyl acetal in refluxing acetic acid affords 1-aryl or 1-alkyl-2-methylthioimidazoles in good yields.Dimethyl N-isopropylcarbonimidodithioate gave 1-isopropylimidazole-2(3H)-thione under similar conditions.

Full text of DOI:10.1055/s-1987-28201

Products guided by the article

Product name:1H-Imidazole, 1-(4-chlorophenyl)-2-(methylthio)-

Cas No:116072-37-8

R&D Labs maybe for 116072-37-8

Shandong Bolode Bio-Technology Co., LTD

Contact:+86-0531-58966870

Address:136 Jingyi Road,Huaiyin District,Jinan,Shandong,China
Tianjin Jingye Fine Chemicals Co., Ltd.

Contact:+86-15722078107; +86-22-26911407

Address:Bohua Fine Chemicals Base of Petrochemical Industry Park, Nanhuan Road, Dagang District, Tianjin, 300271, P. R. China
Zhaodu Fine Chemical Plant

Contact:86-310-8067016

Address:East Fuhua Road,Tiexi Chemical Industrial Estate,Hebei,China
Shanghai Topchem Co., LTD

website:http://www.shtopchem.com/

Contact:0086-0576-87776998

Address:room no 1608,xuhui business building yude road,xujiahui street, xuhui district
wuxi leji biology technology co., LTD

website:http://www.lejibio.com/

Contact:18362718864

Address:The Nanyue Road No. 2, Yixing City, Jiangsu Province

Relevant to this article

Synthesis and reactions of 5-aryl-2-thiophenecarbaldehydes

Doi:10.1007/s10593-008-0135-0
(2008)
Toward synthesis of the isosteric sulfonate analogues of the at-iii binding domain of heparin

Doi:10.1021/ol900952d
(2009)
Synthesis, structures and spectroscopic properties of platinum(II), copper(I) and zinc(II) complexes bearing 4-(p-dimethylaminophenyl)-6-phenyl-2,2′-bipyridine ligand

Doi:10.1016/j.ica.2008.11.020
(2009)
A REGIO AND STEREOSELECTIVE SYNTHESIS OF 2',2'',3',4'-TETRADEUTERIO-2'-DEOXY NUCLEOSIDES

Doi:10.1016/S0040-4020(01)83465-7
(1987)
Inhibition of tRNA-dependent ligase MurM from Streptococcus pneumoniae by phosphonate and sulfonamide inhibitors

Doi:10.1016/j.bmc.2009.03.028
(2009)
Azide Radical Initiated Ring Opening of Cyclopropenes Leading to Alkenyl Nitriles and Polycyclic Aromatic Compounds

Doi:10.1002/anie.202013516
(2021)

Article Doi