Reaction of Dimethyl N-Aryl- and N-Alkylcarbonimidodithioates with Aminoacetaldehyde Diethyl Acetal: A Direct Synthesis of 1-Aryl- and 1-Alkyl-2-methylthioimidazoles

DOI: 10.1055/s-1987-28201

Source and publish data:

Synthesis p. 1136 - 1138 (1987)

Update date:2022-08-05

Topics:

Authors:

Pooranchand, Dinah

Ila, Hiriyakkanavar

Junjappa, Hiriyakkanavar

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Article abstract of DOI:10.1055/s-1987-28201

The reaction of dimethyl N-aryl- or N-alkylcarbonimidodithioates with aminoacetaldehyde diethyl acetal in refluxing acetic acid affords 1-aryl or 1-alkyl-2-methylthioimidazoles in good yields.Dimethyl N-isopropylcarbonimidodithioate gave 1-isopropylimidazole-2(3H)-thione under similar conditions.

Full text of DOI:10.1055/s-1987-28201

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