
Synthesis p. 127 - 129 (1988)
Update date:2022-07-29
Topics:
Simchen, Gerhard
Schulz, Dieter
Seethaler, Toni
Reaction of aliphatic and aromatic aldehydes 4 with the ketene acetal 3 in presence of Lewis acid 2 or zinc bromide affords methyl 2-(methyltrifluoroacetylamino)-3-(trimethylsiloxy)alkanoates 5.By elimination of trimethylsilanol from 5 by means of methane
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(1961)