EINE NEUE SYNTHESE VON VINBLASTIN-DERIVATEN III. SYNTHESE UND REAKTIONEN VON 21,Nb-SECO-CLEAVAMIN-DERIVATEN ALS VORLAUFER ZU 20'-DEETHYL-20'-DEOXYVINBLASTIN UND (+/-)-16α-METHOXYCARBONYL-20-DEETHYL-15,20-DIHYDROCLEAVAMIN

DOI: 10.1016/S0040-4020(01)86862-9

Source and publish data:

Tetrahedron p. 3747 - 3764 (1987)

Update date:2022-08-02

Topics:

Authors:

Schill, Gottfried

Priester, Claus Ulrich

Windhovel, Udo Frank

Fritz, Hans

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Article abstract of DOI:10.1016/S0040-4020(01)86862-9

In a new concept for the synthesis of 20'-deethyl-20'deoxyvinblastine, Nb-seco-cleavamine derivatives 1a,2a are possible precursors.For the synthesis of these compounds the indolizino<5,4-b> indoles 8I,II were treated with benzyl chloroformate/aq. sodium

Full text of DOI:10.1016/S0040-4020(01)86862-9

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