Chiral α-Methyl-homoallylic Alcohols from Yeast-Generated Precursors. Synthesis of (4R,5S) Sitophilure

Article abstract of DOI:10.1246/cl.1988.385

Optically active (3S,4R)-3,4-dihydroxy-4-methyl-6-phenyl-hex-5-ene and (2S,3RS)-2,3-dihydroxy-3-methyl-5-phenyl-pent-4-ene, previously obtained from fermenting baker's yeast reduction of the corresponding ketones, are transformed either into optically act