Synthesis and evaluation of benzophenone oximes derivatized with sydnone as inhibitors of secretory phospholipase A2 with anti-inflammatory activity

DOI: 10.1248/cpb.57.16

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 16 - 21 (2009)

Update date:2022-07-30

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Authors:

Kamble, Ravindra Ramappa

Belgur, Sudha Sathyanarayanrao

Aladkatti, Ravindranath

Khazi, Imthiyaz Ahmed

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Article abstract of DOI:10.1248/cpb.57.16

A series of benzophenone oximes appended with sydnone (3a-h) bearing different substituents on aroyl moiety were synthesized to evaluate in vivo and in vitro for their inhibitory activity against purified phospholipase A ₂ (PLA₂) enz

Full text of DOI:10.1248/cpb.57.16

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