Enantioselective conjugate addition of N-heterocycles to α,β-unsaturated ketones catalyzed by chiral primary amines

Article abstract of DOI:10.1055/s-0029-1216636

A new organocatalytic enantioselective conjugate addition reaction of nitrogen-centered heterocycles with α,β-unsaturated ketones has been developed. Promoted by a chiral cinchona alkaloid derived primary amine, the reaction affords the adducts in moderat