2-(Alkylamino)tetralin Derivatives: Interaction with 5-HT1A Serotonin Binding Sites

DOI: 10.1021/jm00121a045

Source and publish data:

Journal of Medicinal Chemistry p. 253 - 256 (1989)

Update date:2022-07-30

Topics:

Authors:

Naiman, Noreen

Lyon, Robert A.

Bullock, Amy E.

Rydelek, Laura T.

Titeler, Milt

Glennon, Richard A.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00121a045

8-Hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) is a selective 5-HT_1A serotonin agonist.Derivatives of 8-OH-DPAT with amine substituents larger or more bulky than n-propyl appear to be inactive in a presynaptic biochemical assay measuring ag

Full text of DOI:10.1021/jm00121a045

Products guided by the article

Product name:(8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-(4-phenyl-butyl)-amine

Cas No:117145-85-4

R&D Labs maybe for 117145-85-4

hangzhou verychem science and technology co.ltd

website:http://www.verypharm.com

Contact:+86-571-88162785; 88162786

Address:F1502, 753 Shenhua road, Hangzhou, China
Shanghai FWD Chemicals ltd

website:http://www.fwdchem.com

Contact:86-21-54450828

Address:Room 802,Lotus Tower ,159 Tianzhou Road,Xuhui District,Shanghai
KAIYUAN CHEMICAL COMPANY LIMITED.

website:http://www.kaiyuanchem.com

Contact:+86-22-59891255/66/77

Address:B-2205, Kuangshi International Building, Yingbin Road, XiangLuo Bay Business District, Binhai New area, Tianjin, China.
Beijing Cooperate Pharmaceutical Co.,Ltd

website:http://www.cooperate-pharm.com/

Contact:86-01060279497

Address:No.507,Building 4,Tianhua Street, Biomedicine industrial Base
WEIFANG RICHEM INTERNATIONAL LTD

Contact:86-536-2222176

Address:weifang,shandong

Relevant to this article

Synthesis of a new heterocyclic system - Fluoreno[1,2-d]imidazol-10-one

Doi:10.1139/V09-062
(2009)
Coupling reactions of chlorofluoro and perfluoroalkyl iodides

Doi:10.1135/cccc20081719
(2008)
Synthesis of 5-deoxypterocarpens, pterocarpens, and coumestans by intramolecular Heck reaction

Doi:10.1016/j.tetlet.2009.01.004
(2009)
SYNTHESIS OF A POTENT ANTITHROMBIN ACTIVATING PENTASACCHARIDE: A NEW HEPARIN LIKE FRAGMENT CONTAINING TWO 3-O-SULPHATED GLUCOSAMINES

Doi:10.1016/S0040-4039(00)80214-2
(1988)
Structure-activity relationships and cancer-cell selective toxicity of novel inhibitors of glioma-associated oncogene homologue 1 (Gli1) mediated transcription

Doi:10.1021/jm900106f
(2009)
An efficient and facile synthesis of pyrimidine and quinazoline derivatives via one-pot three-component reaction under solvent-free conditions

Doi:10.1002/jhet.43
(2009)

Article Doi