2-(Alkylamino)tetralin Derivatives: Interaction with 5-HT1A Serotonin Binding Sites

DOI: 10.1021/jm00121a045

Source and publish data:

Journal of Medicinal Chemistry p. 253 - 256 (1989)

Update date:2022-07-30

Topics:

Authors:

Naiman, Noreen

Lyon, Robert A.

Bullock, Amy E.

Rydelek, Laura T.

Titeler, Milt

Glennon, Richard A.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00121a045

8-Hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) is a selective 5-HT_1A serotonin agonist.Derivatives of 8-OH-DPAT with amine substituents larger or more bulky than n-propyl appear to be inactive in a presynaptic biochemical assay measuring ag

Full text of DOI:10.1021/jm00121a045

Products guided by the article

Product name:(8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-(4-phenyl-butyl)-amine

Cas No:117145-85-4

R&D Labs maybe for 117145-85-4

Jinan Great Chemical Co.,Ltd.

Contact:+86-531-58668191 58668193 58668196 58661173

Address:No 55,Beixiaoxinzhuang West Street,Jinan City, Shandong Province
SunaTech Inc.

Contact:+86 512 6287 2180

Address:398 Ruoshui Road, Suzhou Industrial Park, Suzhou, Jiangsu, P. R. China
Qingdao S. H. Huanyu Imp. & Exp. Co., Ltd.

Contact:86-532-88250866

Address:Room 615, World Trade Centre Building B, Hongkong Middle Roda 6#, Qingdao, Shandong, China
DU-HOPE INTERNATIONAL GROUP

Contact:+86-25-52346955

Address:199,JIANYE ROAD,NANJING,CHINA
Tianjin Dongchang Fine Chemical Industry Co., Ltd.

Contact:+86-22-29894595

Address:Economic Developing Zone, Ji County, Tianjin, China

Relevant to this article

Synthesis of a new heterocyclic system - Fluoreno[1,2-d]imidazol-10-one

Doi:10.1139/V09-062
(2009)
Coupling reactions of chlorofluoro and perfluoroalkyl iodides

Doi:10.1135/cccc20081719
(2008)
Synthesis of 5-deoxypterocarpens, pterocarpens, and coumestans by intramolecular Heck reaction

Doi:10.1016/j.tetlet.2009.01.004
(2009)
SYNTHESIS OF A POTENT ANTITHROMBIN ACTIVATING PENTASACCHARIDE: A NEW HEPARIN LIKE FRAGMENT CONTAINING TWO 3-O-SULPHATED GLUCOSAMINES

Doi:10.1016/S0040-4039(00)80214-2
(1988)
Structure-activity relationships and cancer-cell selective toxicity of novel inhibitors of glioma-associated oncogene homologue 1 (Gli1) mediated transcription

Doi:10.1021/jm900106f
(2009)
An efficient and facile synthesis of pyrimidine and quinazoline derivatives via one-pot three-component reaction under solvent-free conditions

Doi:10.1002/jhet.43
(2009)

Article Doi