2-(Alkylamino)tetralin Derivatives: Interaction with 5-HT1A Serotonin Binding Sites

DOI: 10.1021/jm00121a045

Source and publish data:

Journal of Medicinal Chemistry p. 253 - 256 (1989)

Update date:2022-07-30

Topics:

Authors:

Naiman, Noreen

Lyon, Robert A.

Bullock, Amy E.

Rydelek, Laura T.

Titeler, Milt

Glennon, Richard A.

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Article abstract of DOI:10.1021/jm00121a045

8-Hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) is a selective 5-HT_1A serotonin agonist.Derivatives of 8-OH-DPAT with amine substituents larger or more bulky than n-propyl appear to be inactive in a presynaptic biochemical assay measuring ag

Full text of DOI:10.1021/jm00121a045

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