Journal of Organic Chemistry p. 5607 - 5616 (1988)
Update date:2022-09-26
Topics: Synthesis Yield Reagents Catalyst Purification Isosteres Dipeptide γ-lactams
Zydowsky, Thomas M.
Dellaria, Joseph F.
Nallans, Hugh N.
Independent five-step syntheses of γ- and δ-lactam-containing dipeptide isosteres, starting from the known compound, (4S)-3-(carbobenzyloxy)-4-(phenylmethyl)-5-oxooxazolidine (3), are reported.Alkylation of 3 with allyl bromide provided the corresponding
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