Alkylation and aldol reactions of acyl and phosphine ligand in (η5-C5H5)Fe(CO)(CH3PPh2)(COCH2R)

Article abstract of DOI:10.1016/0022-328X(93)80429-F

The effect of replacement of triphenylphosphine in CpFe(CO)PPh3(COR) by methyldiphenylphosphine on the reactivity of the acyl ligand attached toFe has been investigated.Reactions of anions generated from complexes (η⁵-C5H5)Fe(CO)(CH3PPh2)COCH3 (5) and (η⁵-C5H5)Fe(CO)(CH3PPh2)COC2H5 (6) with a variety of electrophilic reagents gave mixtures of diastereo- and regio-isomeric products.The proportion of these was found to be independent of the type of base used for deprotonation but dependent on the stoichiometric base-to-complex ratio.The product of benzylation 12gave methyl 3-phenylpropionate after decomplexation with NBS in methanol.