2-Arylamino-3-cyano-5,6,7,8-tetrahydroquinolines and 2-Substituted 1-Aryl-6,7,8,9-Tetrahydropyrimidoquinolin-4-ones Derived Therefrom

Article abstract of DOI:10.1007/BF00475572

Reaction of 2-chloro-3-cyano-5,6,7,8-tetrahydroquinoline with arylamines gives 2-arylamino-3-cyano-5,6,7,8-tetrahydroquinolines, which on reaction with acetic anhydride or benzoyl chloride are converted into the N-acyl derivatives, and on further treatment with hydrogen chloride in anhydrous ethanol, into 2-substituted 1-aryl-6,7,8,9-tetrahydropyrimido<4,5-b>quinolin-4-ones.