Chemistry of Heterocyclic Compounds p. 71 - 73 (1988)
Update date:2022-07-29
Topics:
Gavrilov, M. Yu.
Konshin, M. E.
Reaction of 2-chloro-3-cyano-5,6,7,8-tetrahydroquinoline with arylamines gives 2-arylamino-3-cyano-5,6,7,8-tetrahydroquinolines, which on reaction with acetic anhydride or benzoyl chloride are converted into the N-acyl derivatives, and on further treatment with hydrogen chloride in anhydrous ethanol, into 2-substituted 1-aryl-6,7,8,9-tetrahydropyrimido<4,5-b>quinolin-4-ones.
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