Synlett p. 357 - 358 (1997)
Update date:2022-07-29
Topics:
Saito, Susumu
Ito, Masahiro
Maruoka, Keiji
Yamamoto, Hisashi
Various ketones can be alkylated with tetrahydrofuran (THF) to provide α-siloxybutylated ketones in the presence of a bulky aluminum reagent, lithium diisopropylamide (LDA), and t-butyldimethylsilyl triflate (TBSOTf).
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