Selective Alkylation of Ketones with a Bulky Aluminum Reagent-the THF-TBSOTf System

DOI: 10.1055/s-1997-792

Source and publish data:

Synlett p. 357 - 358 (1997)

Update date:2022-07-29

Topics:

Authors:

Saito, Susumu

Ito, Masahiro

Maruoka, Keiji

Yamamoto, Hisashi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1997-792

Various ketones can be alkylated with tetrahydrofuran (THF) to provide α-siloxybutylated ketones in the presence of a bulky aluminum reagent, lithium diisopropylamide (LDA), and t-butyldimethylsilyl triflate (TBSOTf).

Full text of DOI:10.1055/s-1997-792

Products guided by the article

Product name:Cyclohexanone, 2-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]butyl]-

Cas No:117319-72-9

R&D Labs maybe for 117319-72-9

NEWSTAR CHEM ENTERPRISE LTD.

Contact:0572-2722882

Address:1201,F3,xinghuibandao,
Anhui Sholon New Material Technology Co., Ltd.

website:http://www.sholonchem.com

Contact:+86-550-5261666

Address:4/F Block B, Beijing Chemical Building.No.520 Tianrun Road ,Science & Education Town Wujin District, Changzhou City Jiangsu Province
Shanghai SMEC Trading Co., Ltd.

website:http://www.shanghaismec.com

Contact:+86-21-68811293

Address:ROOM 1101,NO.800 SHANGCHENG RD,SHANGHAI,CHINA
Linyi Shengxin Pharmaceutical R&D Co., Ltd

Contact:+86-18653953873

Address:West First of Yufeng Road, Yishui County
Shanghai Apeptide Co., Ltd.

website:http://www.apeptides.com/en/

Contact:+86-21-60871011

Address:No. 80 Chuanshan Shuyuan Steet,Pudong,Shanghai

Relevant to this article

Novel carbon-carbon bond formation from propargylic alcohols and olefin toward five-membered heterocyclic rings catalyzed by AgSbF₆

Doi:10.1021/ol901270b
(2009)
Titanium hydroamination catalysts bearing a 2-aminopyrrolinato spectator ligand: Monitoring the individual reaction steps

Doi:10.1039/b902038a
(2009)
72-76 Valence Electron Clusters: An Extension of the 16-18 Electron Rule. Synthesis, Crystal Structure, and Solution Dynamics of the Trigonal-Bipyramidal Pentanuclear Clusters (2-) and (2-)

Doi:10.1021/ja00183a027
(1989)
The anticonvulsant activities of functionalized N-benzyl 2-acetamidoacetamides. The importance of the 2-acetamido substituent

Doi:10.1016/S0968-0896(96)00225-8
(1996)
Modification of the butenyl-spinosyns utilizing cross-metathesis

Doi:10.1016/j.bmc.2009.02.036
(2009)
The irreversible thermo-bleaching function of a photochromic diarylethene having trimethylsilyl groups

Doi:10.1039/b822372f
(2009)

Article Doi