Tetrahedron Letters p. 5419 - 5422 (1992)
Update date:2022-08-03
Topics:
Wasserman
Rotello
Krause
The Yoshimura intermediate in the total synthesis of bicyclomycin was prepared by intramolecular addition of an amide to an α,β-diketoamide. The resulting unsymmetrical diketopiperazine was then converted to the diol-ether target.
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