Small Molecule Analogs of Phospholipid-Metal Ion Binding Sites: Synthesis and Molecular Modeling of Cyclohexane-1,2,4-triol Triphosphates

Article abstract of DOI:10.1006/bioo.1994.1014

Four diastereomeric cyclohexane-1,2,4-triol triphosphates were synthesized to serve as small molecule analogs of putative phospholipid-metal ion binding sites. The parent cyclohexane-1,2,4-triols were prepared and phosphorylated. Deprotection of the tris(