AN APPROACH TOWARDS THE FORMATION OF AN ESTER BOND BETWEEN THE PRIMARY HIDROXYL OF A β-D-GALACTOPYRANOSIDE AND 2-AMINOETHYLPHOSPHONIC ACID AND ITS N-METHYL SUBSTITUTED DERIVATIVES

DOI: 10.1016/S0040-4039(00)86687-3

Source and publish data:

Tetrahedron Letters p. 1199 - 1202 (1988)

Update date:2022-09-26

Topics:

Authors:

Dreef, C. E.

Valentijn, A. R. P. M.

Vroom, E. de

Marel, G. A. van der

Boom, J. H. van

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Article abstract of DOI:10.1016/S0040-4039(00)86687-3

An expeditious method for the preparation of the phosphonylating reagent 2-bromo-ethylphosphonic acid is presented.The latter compound as well as salicylchlorophosphite proved to be suitable for the synthesis of methyl O-6-(2'-aminoethyl-phosphonyl)-β-D-g

Full text of DOI:10.1016/S0040-4039(00)86687-3

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