
Tetrahedron Letters p. 309 - 312 (1992)
Update date:2022-08-02
Topics:
Dow, Robert L.
Hain, Marcella A.
Lowe III, John A.
An efficient total synthesis of the glutarimide-based natural product, (±)-epiderstatin 1, in 38% overall yield from acid chloride 4, is described. This study has also allowed for assignment of the C3/C5-relative stereochemistry as trans.
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