
Journal of Organic Chemistry p. 444 - 450 (1989)
Update date:2022-08-05
Topics:
Tanaka, Hideo
Yamashita, Shiro
Yamanoue, Motoi
Torii, Sigeru
A Pb/Al bimetal system was used to carry out reductive addition of tetrachloromethane, tetrabromomethane, bromotrichloromethane, trichloroacetamide, and trichloroacetonitrile to aldehydes.Subsequent 1,2-elimination of the halogen atom and hydroxyl group from the coupling products was also performed with the Pb/Al bimetal system.The technology was successfully applied to stereocontrolled syntheses of ethyl trans- and cis-3-(2,2-dihaloethenyl)-2,2-dimethylcyclopropanecarboxylates.
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