Intramolecular Diels-Alder Reactions of 1,2,4-Triazines. Routes to Condensed Pyrazines via Cycloaddition of Nitrile Dienophiles

Article abstract of DOI:10.1021/jo00267a006

A synthetic route to benzopyrano<3,4-b>pyrazines and the first reported synthesis of the pyrazino<2,3-c>quinoline system are described whereby the fused pyrazine ring is constructed by an intramolecular nitrile/1,2,4-triazine Diels-Alder cycloaddition.Uns