Journal of Organic Chemistry p. 431 - 434 (1989)
Update date:2022-08-02
Topics:
Takeuchi, Hisato
Yanagida, Shun-ichi
Ozaki, Tooru
Hagiwara, Satoshi
Eguchi, Shoji
A new synthesis of oxazoles by an intramolecular aza-Wittig reaction is described.Readily available α-azido ketones 2 were converted to (Z)-β-(acyloxy)vinyl azides 3 by selective enol acylation.These vinyl azides 3 reacted with triethyl phosphite to afford the corresponding oxazole derivatives 5 via the Staudinger reaction, followed by an intramolecular aza-Wittig reaction.In particular, this oxazole synthesis was useful for oxazoles having acid-labile substituents.
View MoreJiangsu Institute of Ecomones Co., Ltd
website:http://www.jsmone.com
Contact:+86-519-82821700
Address:95 Huanyuan N. Road, Jintan, Jiangsu, China
Lishui Nanming Chemical Co., Ltd(expird)
Contact:+86-0578-2134101,2697830
Address:No.19 Tongji Road Shuige Industrial zone
Jinhua City Mingzhu Pharmaceutical Co.,Ltd.
Contact:15857995878 0579-82207761
Address:No.169 Shenze Road, New Area,Jinpan Development Zone, Jinhua
zhenjiang runjing high purity chemical co ltd
Contact:+86-511-83361155
Address:No.8.haixi road,international chemical park
Contact:+49-4101-3053-0
Address:Waldhofstrasse 14 ,25474 Ellerbek Germany
Doi:10.1007/BF00949495
(1981)Doi:10.1002/anie.200460420
(2004)Doi:10.1039/DT9810002573
(1981)Doi:10.1016/S0040-4039(01)82065-7
(1981)Doi:10.1021/ja00375a054
(1982)Doi:10.1016/S0008-6215(00)80669-2
(1981)