Tetrahedron Letters p. 3291 - 3294 (1988)
Update date:2022-08-05
Topics:
Greuter, Hans
Lang, Robert W.
Romann, Andres J.
Silicon induced Reformatskii-Claisen reaction of allyl chlorodifluoroacetate (1) affords 2,2-difluoro-4-pentenoic acid (2) in good yields.Starting from inexpensive chlorodifluoroacetic acid, a variety of useful fluorine-containing synthetic building block
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