
Bulletin of the Chemical Society of Japan p. 2437 - 2442 (1988)
Update date:2022-09-26
Topics:
Kawana, Masajiro
Takeuchi, Kikuko
Ohba, Takayo
Kuzuhara, Hiroyoshi
The reaction of appropiately protected 2'-O-tosyladenosines with methylmagnesium bromide (or iodide) gave 9-(2-deoxy-3-C-methyl-β-D-threopentofuranosyl)adenine after deprotection.The same reaction on 3'-O-tosyladenosine derivatives afforded an epimeric pair of 2'-C-methyl-3'-deoxy sugar nucleosides.The modified structures of the sugar moieties were determined unambiguously.
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