
Organic and Biomolecular Chemistry p. 5653 - 5660 (2018)
Update date:2022-08-04
Topics:
Hu, Zhiyuan
Hou, Jiao
Liu, Jie
Yu, Wenquan
Chang, Junbiao
A transition-metal-free sp3 C-H amination reaction has been established for imidazo[1,5-a]pyridine synthesis employing molecular iodine from 2-pyridyl ketones and alkylamines. In the presence of sodium acetate (NaOAc), the I2-mediate
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