Chemical Communications p. 4251 - 4253 (2009)
Update date:2022-08-04
Topics:
Lu, Hai-Hua
Wang, Xu-Fan
Yao, Chang-Jiang
Zhang, Jian-Ming
Wu, Hong
Xiao, Wen-Jing
A useful Michael addition reaction using nitroalkanes as the nucleophile and 4-oxo-enoates as the Michael acceptor has been disclosed, and the reaction allows expedient access to functionalized chiral γ-keto esters in high yields and excellent enantioselectivities (up to 98% ee), with a low catalyst loading.
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Doi:10.1002/ejoc.201000892
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