Studies on propafenone-type modulators of multidrug-resistance IV): Synthesis and pharmacological activity of 5-hydroxy and 5-benzyloxy derivatives

DOI: 10.1002/ardp.19973301105

Source and publish data:

Archiv der Pharmazie p. 343 - 347 (1997)

Update date:2022-07-30

Topics:

Authors:

Chiba, Peter

Tell, Barbara

Jaeger, Walter

Richter, Elisabeth

Hitzler, Manuela

Ecker, Gerhard

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/ardp.19973301105

A series of 5-hydroxy and 5-benzyloxy analogs of the antiarrhythmic and multidrug resistance (MDR) modulating drug propafenone was synthesized and the MDR-modulating activity of the compounds was evaluated using a daunomycin efflux assay system. The key s

Full text of DOI:10.1002/ardp.19973301105

Products guided by the article

Product name:1-(5-Benzyloxy-2-oxiranylmethoxy-phenyl)-3-phenyl-propan-1-one

Cas No:118635-89-5

R&D Labs maybe for 118635-89-5

Anhui Dexinjia Biopharm Co., Ltd

Contact:+86-531-82375818

Address:9 Hexie Road, kaifaqu, Taihe
Shandong Jincheng Zhonghua Bio-pharmaceutical Co.,Ltd

Contact:+86-533-5415882

Address:Zichuan Economic Development Zone,Zibo City,Shandong Province,China
Yixing Bluwat Chemicals Co., Ltd.

Contact:+86 510 87821568

Address:Yongan Road, Yixing Chemical Industrial Park, Yixing, Jiangsu, China
Changsha Nutritopper Bio Technology Co.,Ltd.

Contact:+86-731-87803543

Address:East 1st Street, Baima Road, Ningxiang County
Shanghai Hohance Chemical Co., ltd

Contact:13914753421

Address:Fl.5；Bld. 70, Lane 1500; Xinfei Road

Relevant to this article

New Glycosidation Reaction 2. Preparation of 1-Fluoro-D-Desosamine Derivative and its Efficient Glycosidation by the Use of Cp2HfCl2-AgClO4 as the Activator

Doi:10.1016/0040-4039(88)85295-X
(1988)
PHENOXIDE AND NAPHTHOXIDE IONS AS NUCLEOPHILES FOR S_RN1 REACTIONS: SYNTHESIS OF BIPHENYL AND PHENYLNAPHTHYL DERIVATIVES

Doi:10.1016/S0040-4039(00)80279-8
(1988)
Identification of N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a potent and selective proviral insertion site of Moloney murine leukemia (PIM) 1, 2, and 3 kinase inhibitor in clinical trials for hematological malignancies

Doi:10.1021/acs.jmedchem.5b01275
(2015)
The passerini reaction with CF₃-carbonyl compounds - Multkomponent approach to trifluoromethyl depslpeptides

Doi:10.1002/ejoc.200900330
(2009)
Synthesis and antitumor activity of novel dithiocarbamate substituted chromones

Doi:10.1016/j.ejmech.2009.04.004
(2009)
Synthesis and molecular structure of tricarbonyl(diphenyl ditelluride)diiodoiron (CO)₃FeI₂(Te₂Ph ₂) and tricarbonyldiiodo[iodo(phenyl)tellurido]iron (CO) ₃FeI₂(PhTeI): First example of the coordination of unstable PhTeI to the transition metal atom

Doi:10.1134/S107032840811002X
(2008)

Article Doi