Studies on propafenone-type modulators of multidrug-resistance IV): Synthesis and pharmacological activity of 5-hydroxy and 5-benzyloxy derivatives

DOI: 10.1002/ardp.19973301105

Source and publish data:

Archiv der Pharmazie p. 343 - 347 (1997)

Update date:2022-07-30

Topics:

Authors:

Chiba, Peter

Tell, Barbara

Jaeger, Walter

Richter, Elisabeth

Hitzler, Manuela

Ecker, Gerhard

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Article abstract of DOI:10.1002/ardp.19973301105

A series of 5-hydroxy and 5-benzyloxy analogs of the antiarrhythmic and multidrug resistance (MDR) modulating drug propafenone was synthesized and the MDR-modulating activity of the compounds was evaluated using a daunomycin efflux assay system. The key s

Full text of DOI:10.1002/ardp.19973301105

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