Antiplatelet activity and TNF-α release inhibition of phthalimide derivatives useful to treat sickle cell anemia

DOI: 10.1007/s00044-019-02371-z

Source and publish data:

Medicinal Chemistry Research p. 1264 - 1271 (2019)

Update date:2022-07-30

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Authors:

Chelucci, Rafael C.

de Oliveira, Isabela J.

Barbieri, Karina P.

Lopes-Pires, Maria E.

Polesi, Marisa C.

Chiba, Diego E.

Carlos, Iracilda Z.

Marcondes, Sisi

Dos Santos, Jean L.

Chung, ManChin

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Article abstract of DOI:10.1007/s00044-019-02371-z

Sickle Cell Anemia (SCA) is one of the most prevalent hereditary hematological diseases worldwide. The disease is characterized by chronic inflammation, hypercoagulable state, and pro-thrombotic profile, which lead the vaso-occlusive process. In this work

Full text of DOI:10.1007/s00044-019-02371-z

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