Synthesis, resolution, and renal vasodilation activity of novel DA1 agonists: 4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline derivatives

DOI: 10.1248/cpb.39.2910

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2910 - 2914 (1991)

Update date:2022-08-04

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Authors:

Anan Tanaka

Tsuzuki Tsuzuki

Yokota Yokota

Yatsu Yatsu

Honda Honda

Asano Asano

Fujita Fujita

Furuya Furuya

Fujikura

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Article abstract of DOI:10.1248/cpb.39.2910

7,8-Dihydroxy-4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline (1) and 4-(3,4-dihydroxyphenyl)-7-hydroxy-8-methyl-1,2,3,4-tetrahydroisoquinoli ne (2) are potent renal vasodilators which selectively stimulate DA₁ (peripheral dopamine recep

Full text of DOI:10.1248/cpb.39.2910

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