SYNTHESIS OF A NOVEL BIFUNCTIONAL CHELATE DESIGNED FOR LABELING PROTEIN WITH TECHNETIUM-99m.

DOI: 10.1016/0040-4039(88)85126-8

Source and publish data:

Tetrahedron Letters p. 3219 - 3222 (1988)

Update date:2022-07-31

Topics:

Authors:

Lever, Susan Z.

Baidoo, Kwamena E.

Kramer, Alfred V.

Burns, H. Donald

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Article abstract of DOI:10.1016/0040-4039(88)85126-8

A novel bifunctional chelate, 1, was designed and synthesized for the facile and efficient incorporation of technetium-99m into biomolecules under mild conditions.The agent features a thiolactone moiety which upon direct protein coupling via amine residue

Full text of DOI:10.1016/0040-4039(88)85126-8

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