A sequence of palladium-catalyzed borylation of allyl acetates with bis(pinacolato)diboron and intramolecular allylboration for the cyclization of oxo-2-alkenyl acetates

Article abstract of DOI:10.1246/cl.1997.811

The cross-coupling reaction of bis(pinacolato)diboron with oxo-2-alkenyl acetates in toluene at 50 °C in the presence of Pd(dba)₂/2 AsPh₃ (3 mol%) to give allylboronates was followed by the intramolecular allylboration at 100 °C. The sequence provided cyclic homoallyl alcohols in high yields.