Bulletin of the Chemical Society of Japan p. 3029 - 3032 (1988)
Update date:2022-08-04
Topics:
Shono, Tatsuya
Matsumura, Yoshihiro
Uchida, Kenshi
Nakatani, Fumihiko
A new method for the synthesis of 2-substituted azetidines has been exploited.The method consists of (1) anodic acetoxylation of 1-(p-tolylsulfonyl)azetidine at the 2-position and (2) subsequent nucleophilic substitution of the acetoxyl group with nucleophiles such as trimethylsilyl cyanide, allyltrimethylsilane, 2-acetoxyfuran, and trimethyl phosphite.
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