A mild procedure for the stereospecific transformation of trans cinnamic acid derivatives to cis β-bromostyrenes

Article abstract of DOI:10.1080/00397919908085891

A new mild procedure has been developed for the synthesis of cis β- bromostyrene analogs with complete Z/E selectivity and good to excellent yields (58.4 - 90.9 %). The process involves carboxyl-halo-elimination of cinnamic acid dibromides by using triethylamine in N,N-dimethylformamide at room temperature. A one-pot procedure has also been described for the direct transformation of cinnamic acids to β-bromostyrenes.

Full text of DOI:10.1080/00397919908085891

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A Mild Procedure for the
Stereospecific Transformation of
trans Cinnamic Acid Derivatives to
cis β-Bromostyrenes
Sun Hee Kim a , Han-Xun Wei a , Steven Willis a & Guigen Li a
a Department of Chemistry and Biochemistry , Texas Tech
University , Lubbock, TX, 79409-1061, U.S.A.
Published online: 17 Sep 2007.
To cite this article: Sun Hee Kim , Han-Xun Wei , Steven Willis & Guigen Li (1999) A Mild
Procedure for the Stereospecific Transformation of trans Cinnamic Acid Derivatives to cis β-
Bromostyrenes, Synthetic Communications: An International Journal for Rapid Communication
of Synthetic Organic Chemistry, 29:23, 4179-4185
To link to this article: http://dx.doi.org/10.1080/00397919908085891
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