REGIO-AND STEREOSELECTIVE ADDITION OF ORGANOLITHIUMS TO NAPHTHALENES. AN EFFICIENT SYNTHESIS OF 1,1,2-TRISUBSTITUTED AND TRANS-2-DISUBSTITUTED DIHYDRONAPHTHALENES

Article abstract of DOI:10.1016/S0040-4020(01)85942-1

The addition of a variety of organolithium reagents to 1-naphthyloxazolines and 2-naphthyloxazolines followed by trapping with electrophiles leads to high yields of the title compounds.Very high stereoselectivity characterizes the present process in that