2(3H)- AND 2(5H)-FURANONES. III. AN EFFICIENT SYNTHESIS AND THE ESCHENMOSER-MANNICH REACTION OF N-SUBSTITUTED 4-AMINO-2(5H)-FURANONE

Article abstract of DOI:10.3987/COM-88-4594

A series of N-substituted 4-amino-2(5H)-furanones (II) was derived from β-tetronic acid (I) by direct action of several aliphatic and aromatic amines.The Eschenmoser-Mannich reaction of II readily gave the corresponding Mannich bases (VI) quantitatively.