Synthesis and structure-activity relationships of cephalosporins with C-3' catechol-containing residues

Article abstract of DOI:10.1021/jm00092a014

Cephalosporins with new catechol substituents at C-3' have been synthesized, including novel compounds with C-3' carbon-carbon bonds. Many of these compounds have high potency against Gram-negative bacteria, in particular against resistant strains like Ps