Chemistry Letters p. 51 - 54 (1989)
Update date:2022-07-30
Topics:
Nakamura, Yushin
The iron complex-substituted psoralen (1) having a moiety capable of photochemically cross-linking to DNA and a DNA cleaving moiety was synthesized.The photoreaction of which is noniron complex of 1, with Co1 E1 plasmid DNA gave the covalently interstrand cross-linked DNA which was cleaved in the presence of FeSO4 and dithiothreitol under air.
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