MOLECULAR AGGREGATION AND ITS APPLICABILITY TO SYNTHESIS. THE DIELS-ALDER REACTION

Article abstract of DOI:10.1016/S0040-4039(00)82104-8

The rates of intermolecular Diels-Alder reactions involving relatively hydrophobic dienes and dienophiles are significantly increased if these reactions are carried out in ethylene glycol.These rate enhancements are most easily understood in terms of aggregation phenomena.