Polarized Ketene Dithioacetals; 71. Synthesis of 2,5-Substituted 3-Bis(methylthio)methylenetetrahydrofurans

Article abstract of DOI:10.1055/s-1988-27689

Synthesis of novel 2,5-substituted 3-bis(methylthio)methylenetetrahydrofurans 4 by oxymercuration-reduction of α-bis(methylthio)methylene-γ,δ-unsaturated alcohols 2 is reported.The carbinols 2 are obtained from the corresponding allyl-(or 2-methyl-2-propenyl)acylketene dithioacetals 1 by sodium borohydride reduction or by treatment with methylmagnesium iodide.