Journal of Medicinal Chemistry p. 1300 - 1307 (1989)
Update date:2022-08-05
Topics:
Woster, Patrick M.
Black, Alison Y.
Duff, Keith J.
Coward, James K.
Pegg, Anthony E.
As part of a continuing search for specific inhibitors of the enzymes involved in polyamine biosynthesis, we have designed and synthesized a multisubstrate adduct inhibitor, S-adenosyl-1,12-diamino-3-thio-9-azadodecane (AdoDATAD), in which critical portio
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