Synthesis of 1-Methoxy-9-mercaptophenoxathiin and the Resolved 1-((N-(Benzyloxycarbonyl)-L-alanyl)oxy)-9-((methoxycarbonyl)dithio)phenoxathiin 10-Oxide Diastereomers. Comments on Improved Methods for Sulfone Reduction

DOI: 10.1021/jo00276a027

Source and publish data:

Journal of Organic Chemistry p. 3647 - 3651 (1989)

Update date:2022-08-04

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Authors:

Kemp, D. S.

Buckler, David R.

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Article abstract of DOI:10.1021/jo00276a027

The syntheses of 1-methoxy-9-mercaptophenoxathiin (5) and the resolved diastereomeric Z-L-alanyl ester sulfoxides 13a and 13b are reported.The synthetic strategy employs the 10-sulfone functionality to direct substitution to the 1- and 9-positions by meth

Full text of DOI:10.1021/jo00276a027

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Product name:1-((N-(benzyloxycarbonyl)-L-alanyl)oxy)-9-((methoxycarbonyl)dithio)phenoxathiin

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