OPTICALLY ACTIVE α-ALKYLSUCCINATES FROM THE STEREOSELECTIVE ALKYLATION OF CHIRAL IMIDE ENOLATES.

DOI: 10.1016/S0040-4039(00)82319-9

Source and publish data:

Tetrahedron Letters p. 6257 - 6260 (1988)

Update date:2022-08-03

Topics:

Authors:

Fadel, Antonine

Salauen, Jacques

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)82319-9

The chiral oxazolidinones 1 and 2 were alkylated by methyl bromoacetate, then subsequent removal of the chiral auxiliary provided readily with high stereoselectivity the α-alkylated succinates 7 and 8.Acyloin condensation and bromination gave the optically active α-t-butylcyclobutanedione 10.

Full text of DOI:10.1016/S0040-4039(00)82319-9

Products guided by the article

Product name:(R)-3-((S)-4-Isopropyl-2-oxo-oxazolidine-3-carbonyl)-5-(4-methoxy-benzyloxy)-pentanoic acid methyl ester

Cas No:120569-42-8

R&D Labs maybe for 120569-42-8

HUNAN CHEMAPI BIOLOGICAL TECHNOLOGY CO.,LTD.

Contact:+86-186-02659358

Address:1004, building 3, Wanke Jinsemaitianyuan, 498 Guitang Road, Yuhua District, Changsha City, Hunan Province, China
Changzhou Sunlight Pharmaceutical Co., Ltd.

Contact:+86-519-83131668;83139028;83138042;83137041

Address:JiuliStreet, Benniu Town Changzhou City, Jiangsu Province
Henan Surface Industry Co Ltd

Contact:86-371-86169316

Address:No.1,Shakou Road,Zhengzhou,China
WEIFANG DERUN CHEMICAL CO.,LTD

Contact:86-536-8956886

Address:weifang
Guangzhou Swan Chemical Co., Ltd.

Contact:+86-20-31075659

Address:NO.301, Hong ba fang investment BLDG 1,Guan chong village,Shiqi town,Panyu district,Guangzhou

Relevant to this article

A rapid and efficient Sonogashira protocol and improved synthesis of free fatty acid 1 (FFA1) receptor agonists

Doi:10.1021/jo902533p
(2010)
A SYNTHESIS OF 2- AND 4(5)-(2-PYRIDINYL)IMIDAZOLES BY PALLADIUM-CATALYSED CROSS-COUPLING REACTIONS

Doi:10.1016/S0040-4039(00)80667-X
(1988)
Asymmetric Synthesis of Multifunctionalized 2,3-Benzodiazepines by a One-Pot N-heterocyclic Carbene/Chiral Palladium Sequential Catalysis

Doi:10.1021/acs.joc.9b02693
(2019)
De novo design of a picomolar nonbasic 5-HT_1B receptor antagonist

Doi:10.1021/jm901200t
(2010)
Microwave assisted [RuCl₂(p-cymene)₂]₂ catalyzed regioselective endo-tandem cyclization involving imine and alkyne activation: An approach to benzo[4,5]imidazo[2,1-a]pyridine scaffold

Doi:10.1039/c4ra02581d
(2014)
A kinetic investigation, supported by theoretical calculations, of steric and ring strain effects on the oxidation of sulfides and sulfoxides by dimethyldioxirane in acetone

Doi:10.1039/b9nj00452a
(2010)

Article Doi