Tetrahedron Letters p. 6257 - 6260 (1988)
Update date:2022-08-03
Topics:
Fadel, Antonine
Salauen, Jacques
The chiral oxazolidinones 1 and 2 were alkylated by methyl bromoacetate, then subsequent removal of the chiral auxiliary provided readily with high stereoselectivity the α-alkylated succinates 7 and 8.Acyloin condensation and bromination gave the optically active α-t-butylcyclobutanedione 10.
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