Hexestrol-linked cytotoxic agents: Synthesis and binding affinity for estrogen receptors

DOI: 10.1021/jm00127a023

Source and publish data:

Journal of Medicinal Chemistry p. 1538 - 1547 (1989)

Update date:2022-08-04

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Authors:

Kohle Kohle

Krohn Krohn

Leclercq

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Article abstract of DOI:10.1021/jm00127a023

With the erythro-hexestrol derivative 2 as the starting material, a variety of cytotoxic linked hexestrol (HEX) compounds were prepared including the HEX-N-lost derivative 36, the HEX-(chloroethyl)nitrosourea 38, the HEX-cyclophosphamide 44, and the HEX-e

Full text of DOI:10.1021/jm00127a023

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