Tetrahedron Letters p. 4665 - 4668 (1988)
Update date:2022-08-04
Topics:
Patel, Dinesh V.
Rielly-Gauvin, Katherine
Ryono, Denis E.
Preparation of the tripeptidic trifluoromethyl alcohol 9 and ketone 10 and their evaluation as renin inhibitors is described.The key step is the Curtius rearrangement of the beta-silyloxy acid 6 prepared via condensation of trifluoroacetaldehyde with the
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