2H-Benzimidazoles (Isobenzimidazoles); Part 4. Nucleophilic Substitution of 5,6-Dichloro-2H-benzimidazole-2-spirocyclohexane

DOI: 10.1055/s-1988-27733

Source and publish data:

Synthesis p. 871 - 876 (1988)

Update date:2022-08-05

Topics:

Authors:

Iddon, Brian

Robinson, Andrew G.

Suschitzky, H.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1988-27733

Reaction conditions for mono- or di-substitution of the chloro substituents in 5,6-dichloro-2H-benzimidazole-2-spirocyclohexane (4) by various nucleophiles (RNH2, R2NH, RS(1-), RO(1-)) are reported.Conversion of 4-morpholino-5-phenylsulphonyl-2H-benzimida

Full text of DOI:10.1055/s-1988-27733

Products guided by the article

Product name:(6-Chloro-spiro[benzoimidazole-2,1'-cyclohex]-5-yl)-(2-iodo-phenyl)-amine

Cas No:120671-52-5

R&D Labs maybe for 120671-52-5

Hangzhou Hysen Pharma co.,Ltd.

website:http://www.hysenpharma.cn/

Contact:0086-571-88298791

Address:#701,Gudun Road Hangzhou
guide(suzhou) fine materials co. ltd

Contact:0512-80972173

Address:21st Building, No.369 Lushan Rd, New District Suzhou China 215129
WUHU HUAHAI BIOLOGY ENGINEERING CO LTD

Contact:+86-553-3836920

Address:7/F NO.82 LAODONG ROAD WUHU CHINA
Suzhou Health Chemicals Co., Ltd.

website:http://www.healthchems.com

Contact:13776257979

Address:No. 338, Jingang Avenue,
Shanghai HengXun Pharmaceutical Tech. Co., Ltd.

Contact:86-86-52730756

Address:Room 603, No. 240, Tianmuzhong Road, Zhabei, Shanghai, China

Relevant to this article

Studies with 2-(acetonylthio)benzothiazole. New routes to isoxazoles, isoxazolo[3,4-b]pyridines, pyrazolo[1,5-a]pyrimidines, pyridines and quinolizines

Doi:10.3184/030823409X464412
(2009)
Simple reagent for the synthesis of oligonucleotides labeled with 3,3,3′,3′-tetramethyl-2,2′-indodicarbocyanine

Doi:10.1007/s11172-006-0230-2
(2006)
Enantioselective nickel-catalyzedanti-arylmetallative cyclizations onto acyclic electron-deficient alkenes

Doi:10.1039/d1cc01166a
(2021)
Remarkable Enhancement of Chemiluminescent Signal by Dioxetane-Fluorophore Conjugates: Turn-ON Chemiluminescence Probes with Color Modulation for Sensing and Imaging

Doi:10.1021/jacs.6b09173
(2016)
Formation and reactivity of the terminal vanadium nitride functionality

Doi:10.1002/ejic.201300178
(2013)
A straightforward synthesis of benzofuran- and indole-substituted 1,2,3-triazoles via click chemistry

Doi:10.1055/s-0029-1217017
(2009)

Article Doi