2H-Benzimidazoles (Isobenzimidazoles); Part 4. Nucleophilic Substitution of 5,6-Dichloro-2H-benzimidazole-2-spirocyclohexane

DOI: 10.1055/s-1988-27733

Source and publish data:

Synthesis p. 871 - 876 (1988)

Update date:2022-08-05

Topics:

Authors:

Iddon, Brian

Robinson, Andrew G.

Suschitzky, H.

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Article abstract of DOI:10.1055/s-1988-27733

Reaction conditions for mono- or di-substitution of the chloro substituents in 5,6-dichloro-2H-benzimidazole-2-spirocyclohexane (4) by various nucleophiles (RNH2, R2NH, RS(1-), RO(1-)) are reported.Conversion of 4-morpholino-5-phenylsulphonyl-2H-benzimida

Full text of DOI:10.1055/s-1988-27733

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