Synthesis of the Novel ?-(Benzyloxymethyl)-Protected Histidine Analogue of Statine. Inhibition of Penicillopepsin by Pepstatin-Derived Peptides Containing Different Statine Side-Chain Derivatives

DOI: 10.1021/jm00127a028

Source and publish data:

Journal of Medicinal Chemistry p. 1571 - 1576 (1989)

Update date:2022-07-30

Topics:

Authors:

Maibaum, Juergen

Rich, Daniel H.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00127a028

The synthesis of aspartic proteinase inhibitors derived from a new histidine side-chain analogue of statine (Sta), (3S,4S)-4-amino-3-hydroxy-5-(imidazol-4-yl)pentanoic acid (HiSta, 20), is reported.Boc-HiSta(BOM)-OMe (7) was prepared in 16percent overall

Full text of DOI:10.1021/jm00127a028

Products guided by the article

Product name:N-Isovaleryl-L-valyl-L-valyl-4(S)-amino-3(S)-hydroxy-5-phenylpentanoic Acid Methyl Ester

Cas No:120742-12-3

R&D Labs maybe for 120742-12-3

lianyungang jinkang pharmaceutical technology co., ltd.

Contact:008651885445517

Address:Jinshan industrial park, Ganyu county, Lianyungang, Jiangsu Province, 222115, China
Xi'an Yuri Solar Co., Ltd

website:https://www.yurisolar.com/en

Contact:86--18092602675

Address:No. 560, East Hangtian Road, Xi'an, China
Fuxin Jintelai Fluorin Chemical Co., Ltd.

Contact:+86-0418-8229599

Address:, 7th Huagong Road, Fluorine industry development zone (Yimatu Town,Fumeng County),Fuxin City, Liaoning Province, China
Qingdao Kingway Pharmtech Co., Ltd.

Contact:86-532-87118899

Address:No. 88, Middle Haixi Road, Jiaonan City, Qingdao, China
puyang hongda shengdao new material co.,ltd.

Contact:+86-393- 4896278

Address:No.29 East Zhongyuan Road

Relevant to this article

Multisignaling detection of cyanide anions based on an iridium(iii) complex: Remarkable enhancement of sensitivity by coordination effect

Doi:10.1039/b9nj00442d
(2010)
N-heterocyclic carbene catalyzed nucleophilic acylation of trifluoromethyl ketimines

Doi:10.1055/s-0029-1217070
(2009)
NOVEL PHENOLICS FROM PHYTOPATHOGENIC FUNGUS HELICOBASIDIUM MOMPA

Doi:10.1246/cl.1989.527
(1989)
Environmentally friendly methods for syntheses of new aromatic bisesters

Doi:10.1080/00397910903219609
(2010)
In situ NMR observation of mono- and binuclear rhodium dihydride complexes using parahydrogen-induced polarization

Doi:10.1021/ic991319r
(2001)
Diphenylprolinol-derived symmetrical and unsymmetrical chiral pincer palladium(II) and nickel(II) complexes: Synthesis via one-pot phosphorylation/metalation reaction and C-H activation

Doi:10.1021/om100234q
(2010)

Article Doi