Steroselective synthesis of some steroidal oxazolines, as novel potential inhibitors of 17α-hydroxylase-C17,20-lyase

DOI: 10.1016/j.steroids.2009.08.001

Source and publish data:

Steroids p. 1025 - 1032 (2009)

Update date:2022-07-30

Topics:

Authors:

Ondre, Dora

Woelfling, Janos

Toth, Istvan

Szecsi, Mihaly

Julesz, Janos

Schneider, Gyula

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Article abstract of DOI:10.1016/j.steroids.2009.08.001

17β-Oxazolinyl steroids 7a-g and 8a-g were synthesized. The Lewis acid-catalysed reactions of (20R)-3β-acetoxy-21-azidomethyl-20-hydroxypregn-5-ene with substituted aromatic aldehydes led to the formation of 3β-acetoxyandrost-5-enes substituted in positio

Full text of DOI:10.1016/j.steroids.2009.08.001

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