Stereoselective Connection of a C2- and a Linear Cn-Unit to a Cyclopropane by a Formal Twofold Nucleophilic Substitution

Article abstract of DOI:10.1055/s-1988-27730

Bicyclo<4.1.0>heptan-7-one O,N-acetals such as 7-methoxy-7-morpholinobicyclo<4.1.0>heptane can be easily converted into 7-substituted 7-(2-oxoalkyl)bicyclo<4.1.0>heptanes via a formal twofold nucleophilic substitution.In the first reaction step, the metho