Thermal Conversion of Fluorinated Azo-compounds into Indazoles: the Case of 2,5,6-Trifluoro-4-(2,4,6-trimethylphenylazo)pyrimidine

Article abstract of DOI:10.1016/S0022-1139(00)81046-5

Thermal dehydrofluorination of 2,5,6-trifluoro-4-(2,4,6-trimethylphenylazo)pirimidine in boiling xylene to 2,4-difluoro-7,9-dimethyl-5H-pyrimido<4,5-c>benzo<1,2>diazepine is accompained by the formation, inter alia, of 5,7-dimethyl-2-(2,5,6-trifluoropyrimidin-4-yl)-2H-indazole.The same product is formed when tetrafluoropyrimidine is treated with 5,7-dimethylindazole.