Scaleable preparation of functionalized organometallics via directed ortho metalation using Mg- and Zn-amide bases

DOI: 10.1021/op9002888

Source and publish data:

Organic Process Research and Development p. 339 - 345 (2010)

Update date:2022-08-04

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Authors:

Knochel, Paul

Wunderlich, Stefan H.

Rohbogner, Christoph J.

Unsinn, Andreas

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Article abstract of DOI:10.1021/op9002888

A range of aryl and heteroaryl organometallics are efficiently prepared in THF Wia directed ortho metalation by using the previously reported amide bases tmpMgCl · LiCl (tmp ) 2,2,6,6-tetramethylpiperidyl), tmp₂Mg · 2LiCl and tmp₂Zn

Full text of DOI:10.1021/op9002888

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