Journal of the American Chemical Society p. 5330 - 5334 (1989)
Update date:2022-08-04
Topics:
Nicolaou, K. C.
Prasad, C. V. C.
Somers, P. K.
Hwang, C.-K.
A well-defined and predictable route to tetrahydrofurans and tetrahydropyrans is described.The method relies on stereo- and regioselective opening of hydroxy epoxides by acid catalysis.The presence of a saturated chain at the remote (from the hydroxy grou
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